Welcome to your Infectious Disease
1.
You are called for a possible hospital admission on a patient in the ED. Upon your evaluation, you determine the patient has a fever, cough, and new pulmonary infiltrate in the right upper lobe of the lung on chest x-ray. Leukocytes are 14,000/mm3. The patient has a history of an abdominal aortic aneurysm measuring 4.6 mm. Which of the following antibiotics is contraindicated in this patient and thus should be avoided?
2.
Which of the following antibiotics is known to cause serotonin syndrome?
3.
The drug ____ inhibits the 30S subunit of bacterial ribosomes while ____ inhibits the 50S subunit:
4.
Which of the following drugs inhibits peptidoglycan synthesis?
5.
Which of the following drugs is bacteriostatic?
6.
A 63-year old female comes to the physician for a routine health exam. He used to be a health care worker and now volunteers in local homeless shelters. During the encounter, you diagnose him with tuberculosis and prescribe him an antimycobacterial drug. On a follow-up appointment 3 months later, he has some new complaints not present before. His mouth feels dry and tingling, along with his feet “feeling funny.” On physical exam, he has decreased sensation to touch in his feet. The patient’s symptoms are most likely a result from which of the following?
7.
Which of the following drugs is the best drug of choice of the options listed for a urinary tract infection in a pregnant patient?
9.
Which of the following is not something a physician would advise in a patient taking Doxycycline?
10.
____ is the drug of choice for treating Listeria.
11.
____ is the drug of choice for treating Syphilis.
12.
Drug of choice for Lyme disease and Rocky Spotted Mountain Fever?
13.
What drug is associated with "gray baby syndrome" which is characterized by pallor, cyanosis, and even death?
14.
Which of the following cephalosporins is effective against Pseudomonas?
15.
Nephrotoxicity and/or ototoxicity is a side effect of which of the following drugs?
16.
What is the most serious side effect associated with penicillins?
17.
What is the most common cause of community acquired pneumonia?
18.
What is the most common cause of atypical pneumonia?
19.
What is the most common cause of hospital acquired pneumonia?
20.
What is the most common cause of meningitis in adults?
21.
What is the most common cause of meningitis in neonates?
22.
What is the most common cause of meningitis in ages 11-17 years?
23.
What is the most common cause of meningitis in the immunocompromised (elderly, HIV, chemotherapy patients)?
24.
Which of the following is not a side effect of isoniazid?
25.
Which of the following drugs is a HIV protease inhibitor?
26.
An HIV patient is being treated for CMV retinitis with ganciclovir. Which of the following drugs should be avoided in this patient as could cause additional myelosuppression?
27.
Which of the following drugs is a mast cell stabilizer?
28.
Which of the following drugs is a HIV reverse transcriptase inhibitor?
29.
Monophosphorylation of this antiviral drug is catalyzed by virus-specified protein kinase phosphotransferase in CMV-infected cells and by viral thymidine kinase in HSV-infected cells.
30.
What is the most common fungal infection in HIV patients?
31.
If you could only pick 1 drug, which would you use to treat a severe systemic Candida infection in a HIV patient?
32.
What antifungal preferentially binds to ergosterol, which thereby alters cellular permeability?
33.
What antifungal inhibits squalene epoxidase?
34.
Treatment of choice for onychomycosis?
35.
What drug is used to treat most causes of malaria, with the exception of some falciparum malaria infections?
36.
What is the only antibiotic of the ones listed that binds the 30S ribosome subunit and is bacteriostatic?
37.
A patient infected with echinococcosis, pinworms, and hookworms is started on albendazole. Which of the following correctly matches the mechanism of action of this drug?
38.
What is the best treatment for a patient infected with schistosomiasis after returning from a mission trip in South America 2 weeks ago?
39.
A sexually active 27-year-old female comes into your clinic with complaints of vaginal discharge. Physical exam reveals a yellow-green, purulent discharge that is foul smelling and an erythematous mucosa with petechiae on the cervix. What is the drug of choice to treat this patient?
40.
A sexually active 27-year-old female comes into your clinic with complaints of vaginal discharge and dyspareunia. Physical exam reveals a white, crumbly, and sticky discharge that is odorless. What is the drug of choice to treat this patient?
41.
A sexually active 27-year-old female comes into your clinic with complaints of vaginal discharge. Physical exam reveals a milky, clear discharge with a fishy odor. What is the drug of choice to treat this patient?
42.
A sexually active 27-year-old female comes into your clinic with complaints of burning sensation while urinating. Upon further exam, a urinary tract infection is diagnosed. Which is a known side effect of the drug of choice for the patient?
43.
A 6-year-old male comes in accompanied by his father with complaints of “itchy butt.” Upon further questioning, you send the family home and instruct them on how to perform a tape test. The father calls you the next day saying it was positive. What is the treatment of choice?
Thank you for you service, Dan 🫡