Drugs of Abuse

Welcome to your Drugs of Abuse

1. 
A patient is brought into the ED by several police officers in restraints. They state he was taken from a party where onlookers stated he was known to take multiple different illicit drugs. It has been 3 hours since then. He is agitated and requires multiple persons to contain him. He states he doesn’t remember or know anything that has happened, and he is innocent. While trying to talk to him, you notice his eyes repetitively move/twitch to the left side uncontrollably. What is the most likely drug related condition he has?
2. 
A patient is brought into the ED by several police officers in restraints. They state she was taken from a party where onlookers stated she was known to take multiple different illicit drugs. While getting the history from the officers, she patient suddenly becomes unresponsive stops breathing. What is the most likely drug condition she has?
3. 
Which of these TWO symptoms of opioid overdose can a patient never develop tolerance to (will always present with no matter how often/much of the drug they intake)? There are TWO CORRECT ANSWERS, pick both from the list.
4. 
Which of the following is a common symptom of opioid withdrawal?
5. 
A 23-year-old female comes into the ED with agitation. She states that she has been feeling more nervous at home recently and has been increasingly trying to calm herself with her “usual activities,” to no avail. She seems anxious and is paranoid that she is not going to get better. On physical exam, you note her heart rate is 120 and her blood pressure is 131/87. She has conjunctival injection in both her eyes and a dry mouth, but everything else is normal. Which of these drugs has the patient likely abused in the last 24 hours?
6. 
A doctor comes to you for a consult on one of her patients. She has a patient diagnosed with alcohol use disorder and wants to prescribe a drug that exacerbates intoxication symptoms and induces negative conditioning. What is the mechanism of action for said drug?
7. 
Which of these is the 1st line treatment for opioid overdose?
8. 
A well-known patient to the emergency department stumbles in with the help of another person. Mr. Buck is a 26-year-old male who has a history of polysubstance abuse. Patient is in the middle of telling you why he is here when he slumps over. The bystander introduces themselves as Mr. Buck’s dealer, and states that he found him lying on the floor next to an empty bottle of pills of unknown origin. On physical exam, Mr. Buck has a heart rate of 40, respiratory rate of 8, blood pressure of 80/40, and temperature of 96.0 Fahrenheit. His pupils are extremely thin and “needle-like” bilaterally. After securing his airway, what is the next pharmacologic step in management for Mr. Buck?

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