DMARDs

Welcome to DMARD/Gout Drugs

1. 
A patient with rheumatoid arthritis comes into your clinic with complaints of fatigue and blood in his pee. He has been treated with methotrexate for 2 years now. On physical exam, you notice hepatomegaly and pallor. What should you give to this patient to alleviate his symptoms?

2. 
A 1 year old baby comes in for his 1 year checkup by his mother. Mom noticed he has been scratching at his face and been more clumsy than usual. She also mentions that his diapers have had a strange color to them, with an almost "brick dust" appearance. On physical exam, you notice a slight delay in all his developmental milestones, a warm tender nodule on his right toe, bruises scattered throughout his body of various stages of healing, and scratches on his cheeks. What is your next step?

3. 
Which of these drugs is inhibits CD20 as its mechanism of action?

4. 
Which of these drugs leads to decreased production of IL-1 and IL-6?

5. 
Which of the following statements best explains why allopurinol is contraindicated with azathioprine?

6. 
A 42-year-old male comes in with intense foot pain. He says he was at a cookout over the weekend, and when he came into work on Monday, his left toe started to hurt. He states there was no trauma, and that the pain is isolated to his toe. He says at the cookout he drank heavily and ate a lot of “bison burgers.” Which of these drugs is the best first choice to treat this patient’s symptoms?

7. 
A 42-year-old male comes in with intense foot pain. He says he was at a cookout over the weekend, and when he came into work on Monday, his left toe started to hurt. He states there was no trauma, and that the pain is isolated to his toe. He says at the cookout he drank heavily and ate a lot of “bison burgers.” Which of these drugs could have prevented these symptoms from occuring?

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